AIT leads to a change in the immune response of T-lymphocytes

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Jan 11, 2022
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The exact mechanism of action of allergen extract during allergen immunotherapy (AIT) course is not fully understood till now.

AIT leads to a change in the immune response of T-lymphocytes, followed by an increase in the level of specific antibodies (IgG4 and/or IgG1 and, and in some cases, IgA) and a decrease in the level of specific IgE. A secondary immune response is an immune deviation of specific T cells from Th2 towards Th1.
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